New Directions in Critical Care Evidence

During the past few decades substantial progress has been made in the care of patients with critical illness. However, several key developments are necessary to further improve outcomes: (1) preclinical studies need realistic models of acute and chronic critical human illnesses; (2) retrospective and prospective observational studies should leverage rapidly evolving digital technology with big-data capability for analysis and patient monitoring; and (3) RCTs should consider novel designs and incorporate appropriate biomarkers to facilitate a personalized approach to evidence development and care delivery. These suggestions are expected to improve acute outcomes and long-term quality of life for critically ill patients and represent a starting point for setting new directions in critical care medicine and research.


Amazing! Life-saving treatments in the critical care arena can have a life-long impact on the patient; imagine a world where phenotypes, biomarkers and genetics help dictate the type of treatment patients receive to ensure a more positive outcome for both the short and long term quality of life for the patient.


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